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This generally well-conducted review found that telmisartan provided better control of blood pressure than losartan in hypertensive patients without an increased risk of associated adverse events.

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After a 2-week run-in period, each of the 4 ARBs was assigned to subjects who were diagnosed as having hypertension on the basis of home BP and who were over 30 years old.

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The number of deaths that would be required to detect, with 90 percent power, a 20 percent difference between the death rate with valsartan and that with placebo (estimated at 12 percent per year) was calculated to be 906.

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