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I've been on Gleevec since Aug. 24 2001 for Chronic Myelogenous Leukemia. I've had no side effects with it. The only side effect I had is when the doctor had me on both Gleevec and interferon it caused my heart function to drop. They took me off the interferon and heart function was normal. Been in remission for 11 years.

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I am so thankful for Gleevec! I did have some side-effects but prior to Gleevec, taking interferon and hydroxyurea led to much more severe side effects. I had aching limbs, and I now have a skin reddening/rash--like rosacea on my cheeks and my upper arms are reddish--like a mild sunburn. I have tummy issues now--gurgling, diarrhea, cramping, etc., but they are easily managed with imodium. Gleevec has extended my survival and I had the honor of meeting Dr Druker who developed the drug, at Oregon Health and Science University. He was absolutely wonderful as was the care I received there.

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At ASCO 2007 the results of treating 69 patients with chronic phase of CML or ALL who had relapsed or were resistant to Gleevec with bosutinib were presented.

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Therapy should be initiated by physician experienced in the treatment of patients with chronic myeloid leukemia.

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MPD, or ASM and heart involvement, cases of heart disease have been associated with the initiation of GLEEVEC therapy.

And Druker has developed other drugs for when resistance persists, always staying one step ahead of the cancer.

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Recognition of the pivotal role of the BCR-ABL protein in CML led to the development of Gleevec which blocks the activity of this protein.

The other fellows, too, were witnessing similarly dramatic responses in their patients.

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