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I have essential thrombocytemia and have been on Hydrea for more than 5 years. The dosage differs from time to time, according to my blood tests. Actually I undergo blood tests every months since the time I was diagnosed with the disease. This is not the first thrombocytemia medication I am on, but this is by far the best one. With Hydrea I have least side effects and it provides excellent results on my platelets level. However I have some nausea and occasional headaches I feel much better with Hydrea than with any other med. I do hope that one day I will be able to find a more effective treatment that will help me conquer the illness but in general I am happy with Hydrea as it makes my quality of life so much higher. My doctor is also satisfied with the results we achieve when on Hydrea and he plans to continue this treatment course. I wish him lots of luck!)
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This harm could not be assessed in trials that enrolled patients with chronic myeloid leukemia because acute leukemia was evaluated as an outcome rather than as a medication-related toxicity.
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The contribution of cyclooxygenase-1 and -2 to persistent thromboxane biosynthesis in aspirin-treated essential thrombocythemia: implications for antiplatelet therapy.
Interferon α therapy for patients with essential thrombocythemia.
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Whether these recommendations also apply to polycythemia vera and essential thrombocythemia patients is unclear.
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Ex vivo studies of mononuclear cells taken from patients on hydroxyurea did not demonstrate increased genomic instability that might contribute to teratogenesis or leukemogenesis.
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Furthermore, all the six sufferers who were handled with a mixture of HCQ and azithromycin tested damaging on Day 6. The authors argue that this finding speaks to the effectiveness of HCQ and a potential synergistic impact of its combined treatment with azithromycin.
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